Glutamate Transporter 1-mediated Antidepressant-like Effect in a Rat Model of Chronic Unpredictable

• 作 者: 陈建新 姚丽华 徐碧波 钱坤 王惠玲 刘忠纯 王晓萍 王高华
• 机 构: DepartmentofPsychiatry,DepartmentofPsychology,DepartmentofObstetricsandGynecology
• 出 处: 华中科技大学学报：医学英德文版
• 发表日期: 2014年6期
• 关键词: 谷氨酸转运体 大鼠模型 抑郁症 慢性 应激 介导 BLOT分析 CUS chronic unpredictable stress glutamate tran
• 基金项目: This project was supported by the Key Technology Research of Major Mental Illness Prevention and Treatment for the Bar- riers to the Recognition and Prevention of Depression and Anxiety in the General

In recent years, more attention has been paid to the role of the glutamate transporter 1(GLT-1, EAAT2) in major depressive disorder(MDD). However, experimental data on brain GLT-1 levels are, to some extent, inconsistent in human postmortem and animal stu