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我院自1960年8月至1995年7月,共行死婴尸检751例,检出畸形儿233例(占31.03%),751例中围产儿为716例,围产儿畸形219例(占30.59%)。依照系统畸次及疾病畸次进行统计,结果显示多系统畸形103例,单系统畸形129例,联体畸形1例。消化系统、心血管系统和神经系统占前3位,三者占系统畸次的54.3%,最常见的畸形依次为脑脊髓膜膨出和/或脊柱裂、脑积水、房缺、室缺、肺的发育异常、小肠憩室、无脑儿、唇腭裂等。103例多系统畸形中,2系统畸形为57例,3、4、5、6个系统畸形依次为57例、29例、11例、5例和1例。心血管系统畸形常与消化、呼吸和体腔系膜系统畸形合并出现,神经系统畸形常与颜面、颈部、四肢畸形并存。随着年代变迁,神经系统畸形所占比例呈上升趋势,(x2=16.26,P<0.001),心血管系统畸形呈下降趋势,(x2=9.704,P<0.05),差异均具有统计学意义。
Our hospital from August 1960 to July 1995, a total of 751 dead autopsy, detection of deformed children in 233 cases (31.03%), 751 cases of perinatal 716 cases, 219 cases of perinatal malformations ( Accounting for 30.59%). According to the statistics of system abnormality and disease malocclusion, the results showed that 103 cases were multi-system deformity, 129 cases were single system deformity and 1 case was deformity. The digestive system, cardiovascular system and nervous system accounted for the top three, the three accounted for 54.3% of the system malformations, the most common deformities followed by the encephalocele bulging and / or spina bifida, hydrocephalus, atrial septal defect, Room, lung dysplasia, intestinal diverticulum, no brain children, cleft lip and palate. Among the 103 cases with multiple system deformities, 57 cases were 2 system malformations, and 3, 4, 5, 6 system malformations were 57 cases, 29 cases, 11 cases, 5 cases and 1 case. Frequent cardiovascular system deformity and digestion, respiratory and systemic mesangial system deformity merger, nervous system deformity and the face often, neck, limb deformities co-exist. With the changes of age, the proportion of nervous system malformations showed an upward trend (x2 = 16.26, P <0.001), and the deformity of cardiovascular system showed a decreasing trend (x2 = 9.704, P <0.05) , The differences were statistically significant.