论文部分内容阅读
人淋巴细胞SCE频率的测定作为一种体内或体外接触潜在致突变物的非常敏感的应答指标,已被愈来愈广泛地用于遗传毒理学的研究.然而,除肿瘤治疗外,因体内接触致突变物的剂量通常较低,所以观测到的SCE频率往往不增加或仅有轻度增加,造成实验组与对照组之间的差异很小,只有进行统计学处理,才能明确其结果.此外,由于各个实验室的培养条件及血液标本本身的原因.培养的人淋巴细胞SCE正常值可存在明显的差异.本文则通过对2例正常献血者在约一年的时间内,进行重复检测,探讨人淋
Determination of the human lymphocyte SCE frequency as a very sensitive indicator of response to potential mutagens in vivo or in vitro has been increasingly used in genotoxicity studies, however, with the exception of oncological treatments, The dose of the mutagen is usually low, so the observed frequency of SCE often does not increase or only slightly increases resulting in small differences between the experimental and control groups, and the results can only be determined by statistical processing. , Due to the various laboratory culture conditions and the reasons for the blood specimen itself cultured lymphocytes SCE normal there may be significant differences in this article by two normal blood donors in about a year’s time to repeat the test, Explore people shower