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脑血管病是目前威胁人类健康的主要疾病之一,缺血性卒中占大多数。近年来临床发现自然绝经期前、绝经期后的妇女与同年龄组的男性脑缺血发病率不同。据此推测雌激素的水平与缺血性卒中的发生、发展有一定关系。虽然对雌激素与脑血管病的研究甚少,但有一点可以肯定,那就是雌激素对脑缺血有保护作用。1 雌激素的产生、生理作用及代谢天然雌激素是甾体类固醇激素,人体内有雌二醇、雌三醇、雌酮三种,以雌二醇为主,除主要由卵巢分泌
Cerebrovascular disease is currently one of the major diseases that threaten human health. Ischemic stroke accounts for the majority. In recent years, clinical findings in menopausal women before menopause and men of the same age group have different incidence of cerebral ischemia. This suggests that the level of estrogen and ischemic stroke occurrence and development have a certain relationship. Although little is known about estrogen and cerebrovascular disease, one thing is certain: that is, estrogen has a protective effect on cerebral ischemia. 1 estrogen production, physiological role and metabolism Natural estrogen is a steroid hormone, the body of estradiol, estriol, estrone three kinds of estradiol-based, in addition to the main secretion by the ovary