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本文通过对启东、泰兴１４０例原发性肝细胞癌（ＨＣＣ）和２４７例对照血清中ＨＢＶ、ＨＣＶ指标和分析，重点评价ＨＣＶ致ＨＣＣ的病因学作用。结果显示：ＨＢＶ各标志物和抗－ＨＣＶ的阳性率均以病例组显著高于对照组．且有统计学极显著差异．Ｐ＜０．００１，ＯＲ值在２．６３～９．６３之间；非条件Ｌｏｇｉｓｔｉｃ回归分析可见：具有不同ＨＢＶ标志物者患ＨＣＣ的ＯＲ值和ＰＡＲ可相差数倍，以ＨＢｓＡｇ阳性者的危险性最大．ＯＲ和ＰＡＲ分别为９．４９和５８．７９％；抗－ＨＣＶ的ＯＲ值也较高，在４．１～４．９之间．说明ＨＣＶ致ＨＣＣ的相对危险性是较高的．由于人群抗－ＨＣＶ阳性率普遍较低，所以其ＰＡＲ－值也相对较低（１１．４～１１．９％）．但抗－ＨＣＶ与ＨＢｓＡｇ重叠感染对ＨＣＣ的发生有明显的协同作用，ＯＲ值高达７０．７１．因此，ＨＣＶ致ＨＣＣ的危险性也是不容忽视的。
In this paper, 140 cases of primary hepatocellular carcinoma (HCC) and 247 cases of control serum HBV and HCV in Qidong and Taixing were analyzed, and the etiological role of HCV in HCC was evaluated. The results showed that the positive rates of HBV markers and anti-HCV were significantly higher in case group than in control group. There are statistically significant differences. P <0.001, OR between 2.63 ~ 9.63; unconditional Logistic regression analysis showed that: patients with different HBV markers of HCC and OR can be a multiple of several times the risk of HBsAg-positive Sex most. OR and PAR were 9.49 and 58.79%, respectively. The OR of anti-HCV was also higher between 4.1 and 4.9. This shows that the relative risk of HCC caused by HCV is high. Due to the generally lower prevalence of anti-HCV in the population, its PAR-value is also relatively low (11.4-11.9%). However, anti-HCV and HBsAg overlap infection has a significant synergistic effect on the occurrence of HCC, OR value of up to 70.71. Therefore, the risk of HCC caused by HCV can not be ignored.