论文部分内容阅读
目的:通过对共和县2010年—2012年儿童免疫规划四种疫苗免疫后抗体阳性率进行监测分析,总结免疫效果。方法:选取共和县2010年—2012年10个月~1岁1 042名接种4种疫苗的儿童作为研究对象,应用乳胶法检测抗-HBs,采用酶联免疫法检测百日咳、白喉、破伤风、麻疹、脊灰IgG抗体。记录相关数据,进行统计分析。结果:被监测的1 042例儿童中,4种疫苗6种疾病的平均抗体阳性率分别为:抗-HBs 84.93%、百日咳97.50%、白喉97.22%、破伤风97.50%、麻疹98.75%、脊灰99.04%,抗-HBs、麻疹、脊灰抗体阳性率间无明显差异,百日咳、白喉、破伤风抗体阳性率间差异明显。结论:通过3年对10个月至1岁儿童4种疫苗6种抗体检测,乙肝疫苗抗体阳性率较低,其它疫苗抗体阳性率均维持在较高水平,今后须加强高质量的乙肝疫苗接种。
OBJECTIVE: To monitor and analyze the positive rate of antibodies after immunization of four vaccines of Republic of China from 2010 to 2012 in Children’s Republic of China, and summarize the immune effect. Methods: A total of 1,042 children vaccinated with 4 vaccines from 10 to 10 years old in Gonghe County from 2010 to 2012 were enrolled in this study. The anti-HBs were detected by latex method. Pertussis, diphtheria and tetanus were detected by enzyme-linked immunosorbent assay (ELISA) Measles, polio IgG antibody. Record the relevant data for statistical analysis. Results: Among the 1042 children tested, the average antibody positive rates of the four vaccines were 84.93% for anti-HBs, 97.50% for pertussis, 97.22% for diphtheria, 97.50% for tetanus, 98.75% for measles, polio 99.04%, there was no significant difference between anti-HBs, measles and poliovirus positive rate, and there was significant difference between the positive rate of pertussis, diphtheria and tetanus antibody. CONCLUSIONS: The positive rate of antibody against hepatitis B vaccine is low and the positive rate of other vaccine antibodies is maintained at a high level by testing 6 kinds of antibodies against 4 vaccines of 10 months to 1 year old in 3 years. In the future, it is necessary to strengthen high-quality hepatitis B vaccination .