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我国是世界结核病大国之一,近年来,随着环境污染的进一步加重,结核病的发病率与死亡率亦有上升趋势。抗结核药物治疗是最有效的治疗肺结核的途径,却又具有不同程度致肝功能损伤,用药时间越长肝功能损伤越严重[1]。有文献报道称抗结核药物引起的不良反应发生率平均为12.6%[2],因此,肝损伤在抗结核用药治疗中不可忽视的重要因素之一[3]。为
In recent years, with the further increase of environmental pollution, the morbidity and mortality rate of tuberculosis have also risen in our country. Anti-TB drug treatment is the most effective way to treat tuberculosis, but with varying degrees of liver damage, the longer the time of treatment, the more serious liver damage [1]. It has been reported in the literature that the average incidence of adverse reactions caused by anti-TB drugs is 12.6% [2]. Therefore, one of the most important factors that can not be ignored in the treatment of anti-tuberculosis drugs is liver injury [3]. for