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关于普鲁卡因过敏及皮试问题提出以下看法供为参考: 一、该剂过敏率极低进入人体后短时间内即被假胆硷酯酶所破坏。我们25年来所遇“真正”过敏者仅为个别病例。二、误诊率很高,常见其他反应误为普鲁卡因过敏者有以下数种: 1.大剂量高浓度误入血管(或静脉窦)引起中毒症状者(我院一例2％液30毫升左右,阴茎包皮手术致严重惊厥),少量静脉注射亦易头晕、心慌、唇麻。 2.麻药成药内已加肾上腺素者,如牙科所用,曾见高血压病例反应极为严重。
On the procaine allergy and skin test questions put forward the following views for reference: First, the agent has a very low rate of allergy into the human body within a short time by the pseudo-cholinesterase destroyed. We have only had “real” allergies in our 25-year history as individual cases. Second, the misdiagnosis rate is high, common other reactions mistaken for procaine allergy have the following kinds: 1. High-dose high concentration into the blood vessels (or sinus) caused by symptoms of poisoning (a hospital 2% solution 30 ml About penile foreskin surgery caused severe seizures), a small amount of intravenous injection is also easy to dizziness, palpitation, lip Ma. 2. Anesthetic drugs have been added adrenaline, such as dentistry, have seen the reaction of hypertensive cases is extremely serious.