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肝脏是人体内再生能力最为旺盛的一个器官,切除大鼠三分之二肝脏,残肝在10～20天便能恢复原有大小。肝的再生机能受到体内某些物质的影响和调节,这个问题随着肝脏外科的发展,日益受到人们的重视。近十余年来,大量的基础和临床研究表明,肝脏正常形态和机能的维持以及肝细胞的再生均与体内存在的某些肝营养因子(Hepatotrophic factors)密切有关。肝营养因子人们早就发现,血液中有某种物质可促进肝细胞的再生。Bucker切除动物的部分肝组织,发现残肝的截面上再生并不是均匀的,而是沿着血流供应的方向
The liver is the most regenerative organ in the human body, removing two-thirds of the liver in rats, residual liver in 10 to 20 days will be able to restore the original size. Liver regeneration is influenced and regulated by some substances in the body. With the development of liver surgery, the problem is receiving more and more attention. In the recent ten years, a large number of basic and clinical studies have shown that the maintenance of normal liver morphology and function and the regeneration of hepatocytes are closely related to the presence of certain hepaticotrophic factors in vivo. Hepatic trophic factor It has long been discovered that there is a substance in the blood that promotes the regeneration of hepatocytes. Bucker excised some of the animal’s liver tissue and found that the regeneration of the residual liver cross section is not uniform, but along the direction of blood flow