毛麝香中一种单萜过氧化物

• 出 处: 国外医学(中医中药分册)
• 发表日期: 1994年01期
• 关键词: 单萜 干燥品 毛麝香 光谱数据 化学结构 硅胶柱 索氏提取器 乙酸乙醋

收集毛麝香(Adenosma caeruleum)地上部分的干燥品(1kg),在索氏提取器中,以氯仿(51)提取10小时。减压下回收溶剂,残渣经硅胶柱反复层析,用汽油-乙酸乙酯(7:3)洗脱得化合物3(10mg,0.001％),而用乙酸乙酯-甲醇(19:1)洗脱得单萜1(180mg,0.018％)和2(20mg,0.002％)。在分析光谱数据尤其是2DNMR光谱数据的基础上,确定了其化学结构。

The dried aerial parts of the aerial parts of Adenosma caeruleum (1 kg) were collected and extracted with chloroform (51) for 10 hours in a Soxhlet extractor. The solvent was recovered under reduced pressure and the residue was repeatedly chromatographed on a silica gel column eluting with petrol-ethyl acetate (7:3) to give compound 3 (10 mg, 0.001%), which was washed with ethyl acetate-methanol (19:1). Removed monoterpene 1 (180 mg, 0.018%) and 2 (20 mg, 0.002%). Based on the analysis of spectral data, especially 2D NMR spectral data, the chemical structure was determined.