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自1992年10月～1999年12月,我们应用大剂量纳洛酮治疗急性CO中毒26例,配合高压氧仓,减少了迟发性脑病及脑梗死等后遗症的发生,效果满意,报告如下。1 临床资料1.1 一般资料 CO中毒者52例均伴有不同程度的昏迷,昏迷时间均为4～5个小时,随机分为纳洛酮治疗组和常规组。治疗组26例,男15例,女11例,平均年龄37.2岁;常规组26例,男14例,女12例,平均年龄38岁。1.2 诊断 (1)有明确CO气体中毒接触史及患此病的接触时间。(2)均有昏迷病史,均有强烈眩晕、恶心呕吐、皮肤粘膜樱桃红色、视力模糊、胸闷、心悸和憋喘,严重者有呼吸困难、抽搐、休克及感觉运动障碍等症状及体征。(3)排除其他疾病导致的昏迷以及神经系统病史。(4)快速检测碳氧红蛋白的含量增高
From October 1992 to December 1999, we applied high-dose naloxone to treat 26 cases of acute CO poisoning. Combined with hyperbaric oxygen chamber, we reduced the occurrence of sequelae, such as delayed encephalopathy and cerebral infarction. The results were satisfactory. The report is as follows. 1 Clinical data 1.1 General information CO poisoning in 52 cases were associated with varying degrees of coma, coma time are 4 to 5 hours, were randomly divided into naloxone treatment group and conventional group. The treatment group of 26 patients, 15 males and 11 females, mean age 37.2 years; conventional group of 26 patients, 14 males and 12 females, mean age 38 years. 1.2 Diagnosis (1) There is a clear CO gas poisoning exposure history and exposure to the disease contact time. (2) Both have a history of coma, both have strong dizziness, nausea and vomiting, skin and mucous membrane cherry red, blurred vision, chest tightness, palpitations and wheezing, severe dyspnea, convulsions, shock and sensory dyskinesia and other symptoms and signs. (3) exclude other diseases caused by coma and nervous system history. (4) rapid detection of increased levels of carboxyhemoglobin