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目的 :研究骨髓转移瘤的临床和病理学特点。方法 :骨髓活检塑料包埋切片 ,H- Gmiesa- E,Gomori,PAS,Alcin blue染色。结果 :6 6例骨髓转移瘤中 ,低分化腺癌 42例、黏液腺癌 6例、黏液细胞癌 3例、低分化鳞癌9例、巨细胞癌 2例、未分化癌 2例、恶性黑色素瘤 1例、恶性纤维组织细胞瘤 1例。临床表现以贫血最常见(95 .1% ) ,其次为血小板减少 (5 9.5 % )和骨痛 (5 7.4% )。临床初诊常误诊为多发性骨髓瘤和其他血液病 ,仅 17例查到原发瘤部位 (2 5 .8% )。对转移瘤的病理与临床特点作了讨论。结论 :对于原发瘤尚不明确而已发生骨髓转移的肿瘤 ,骨髓活检具有重要诊断价值。
Objective: To study the clinical and pathological features of bone marrow metastases. METHODS: Bone marrow biopsy plastic-embedded sections, H-Gmiesa-E, Gomori, PAS, Alcin blue staining. RESULTS: Of the 66 bone marrow metastatic tumors, there were 42 poorly differentiated adenocarcinomas, 6 mucinous adenocarcinomas, 3 mucinous cell carcinomas, 9 poorly differentiated squamous cell carcinomas, 2 giant cell carcinomas, 2 undifferentiated carcinomas, and malignant melanin. One case of tumor and one case of malignant fibrous histiocytoma. Clinical manifestations were most common with anemia (95.1%), followed by thrombocytopenia (59.5 %) and bone pain (5 7.4%). The initial clinical diagnosis was often misdiagnosed as multiple myeloma and other hematological diseases. Only 17 cases (25.8 percent) of primary tumors were found. The pathological and clinical features of metastases were discussed. Conclusion : Bone marrow biopsy has important diagnostic value for tumors with unclear primary tumors and bone marrow metastases.