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目的探讨清洁腮腺手术围术期抗菌药物对术后组织愈合的影响。方法回顾性分析260例腮腺肿块手术治疗患者的临床资料。260例分为A组(使用抗菌药物,119例)和B组(未使用抗菌药物,141例)。A、B组又分为有感染风险因素的A1组(37例)、B1组(42例)和无感染风险因素的A2组(82例)、B2组(99例)。结果 A、B组在术后72h内体温升高、切口裂开、线头反应、涎瘘和手术部位感染方面比较均无统计学差异(P>0.05)。A1组切口裂开发生率高于A2组(16.2%vs.2.4%)(P<0.05);B1组切口裂开发生率高于B2组(19.0%vs.3.0%)(P<0.01)。结论清洁腮腺手术可以不使用抗菌药物预防术后感染,也并不会影响术后的组织愈合。
Objective To investigate the effect of perioperative antibiotic treatment on the healing of postoperative tissue in the parotid gland. Methods A retrospective analysis of 260 cases of parotidectomy surgery in patients with clinical data. 260 cases were divided into group A (antibacterials, 119 cases) and group B (no antibacterials, 141 cases). Group A and B were divided into group A1 (n = 37), group B1 (n = 42), group A2 (n = 82) and group B2 (n = 99) without risk factors. Results In groups A and B, there was no significant difference in body temperature, incision, incision, salivary fistula and surgical site infection within 72 hours after operation (P> 0.05). The incidence of incision rupture in group A1 was higher than that in group A2 (16.2% vs.2.4%) (P <0.05). The incidence of incision rupture in group B1 was higher than that in group B2 (19.0% vs.3.0%, P <0.01). Conclusion Clean parotid gland surgery can prevent the use of antibacterial drugs to prevent postoperative infection, it will not affect the postoperative tissue healing.