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肾移植过程中肾脏可受到三种损害。1)为热缺血,与临床情况有关。2)为冷缺血,主要发生在2～50小时的肾保存阶段。由于在低温下大多数代谢反应明显下降,故损害较轻。3)为肾再灌注所致,如能处理得当可降低移植后急性肾衰的发生率。缺血时肾细胞进行厌氧代谢,储存的高能磷酸被消耗殆尽,积聚的中间代谢产物将与分子氧发生反应。再
The kidneys can suffer three types of damage during kidney transplantation. 1) for the warm ischemia, and clinical conditions. 2) cold ischemia, mainly occurs in 2 to 50 hours of renal preservation phase. Lesser damage is due to the significant reduction in most metabolic reactions at low temperatures. 3) caused by renal reperfusion, if properly managed to reduce the incidence of acute renal failure after transplantation. Ischemia kidney cells for anaerobic metabolism, storage of high-energy phosphoric acid is depleted, the accumulation of intermediate metabolites will react with molecular oxygen. again