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Male patient,1 year and 6 months old,visited on January l,2012.Chief complaint:fever for 4 days,skin rashes for 3 days,intermittent convulsion and vomiting for 2 days.Present medical history:the child got fever 4 days ago without apparent inducers and the temperature was up to 40 ℃.By the local clinical treatment with intramuscular injection of antipyretic drug (definite medicine unknown),the temperature was recovered normal,but repeated easily.3 days ago,the family member found that the child had a few rashes on the hands and feet,which was treated with intravenous infusion in local clinic (definite medicine unknown),but the efficacy was not satisfactory.Two days ago,the child got intermittent convulsion and vomiting of the gastric stuff,non-projectile vomiting and appetite reduced by 1/3 as compared with the normal.In the local Maternal and Child Care Service Center,the throat swab test showed:mycoplasma positive,leukocyte positive;the blood routine test suggested:leukocyte count:12.22 × 109/L.