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目的观察高压氧对老年代谢综合征危险因素的影响。方法共选取60~76岁患者61例,将其随机分为高压氧组(0.2MPa压力下吸纯氧)、常压氧组(常压下吸纯氧)及常压空气组。各组患者分别于治疗前及治疗3个疗程后对其代谢综合征危险因素进行动态观察及组内、组间比较。结果治疗前各组患者代谢综合征危险因素发病率间差异均无统计学意义;各组患者经相应治疗后,发现HBO组空腹血糖、血流变、血压、胰岛素抵抗与其治疗前及其他2组治疗后比较,差异均有统计学意义(P<0.05);血脂水平也有一定程度改善;其它2组患者各项观察指标治疗前、后比较,差异均无统计学意义(P>0.05)。结论HBO治疗具有控制血糖、调整血压、降低血液黏稠度、调整血脂紊乱、改善胰岛素抵抗等功效,对抑制老年代谢综合征危险因素的发生具有积极作用。
Objective To observe the effect of hyperbaric oxygen on the risk factors of metabolic syndrome in the elderly. Methods A total of 61 patients aged 60-76 years were selected and randomly divided into hyperbaric oxygen group (pure oxygen at 0.2MPa pressure), normobaric oxygen group (normobaric oxygen inhalation) and normal pressure air group. Each group of patients before and after treatment of three courses of metabolic risk factors for dynamic observation and intra-group comparison. Results Before treatment, there was no significant difference in morbidity of metabolic syndrome between the two groups. After treatment, the fasting blood glucose, blood rheology, blood pressure, insulin resistance of HBO group were significantly higher than those before treatment and other two groups After treatment, the differences were statistically significant (P <0.05); blood lipid levels also improved to some extent; the other two groups of patients before and after treatment, the difference was not statistically significant (P> 0.05). Conclusion HBO treatment has the effects of controlling blood sugar, adjusting blood pressure, lowering blood viscosity, adjusting blood lipid disorder, improving insulin resistance and other effects, inhibiting the occurrence of risk factors of elderly metabolic syndrome.