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为了解北京地区不同人群HCV感染状况及其基因型.对来自北京地区不同人群1072份血清分别进行了抗HCVELISA和HCVRNA基因型检测。结果显示.该地区自然人群、急性肝炎、慢性迁延性肝炎、慢性活动性肝炎、肝硬化和肝细胞癌患者中抗-HCV阳性率分别为1.7%、8.3%、12.4%、27.6%、38.1%及20.7%,HCV感染者中有56.4%具有输血、献血及使用血制品史.提示经血传播是该地区HCV的主要感染途径.该地区人群HCV基因型分布以Ⅱ型为主(77.4%).其次为Ⅲ型(17.8%).并有少量ⅡⅢ混合型(4.8%)。
To understand the status of HCV infection and its genotype in different populations in Beijing. The anti-HCV ELISA and HCV RNA genotypes were detected in 1072 serum samples from different populations in Beijing. The results show. The positive rates of anti-HCV in the natural population, acute hepatitis, chronic persistent hepatitis, chronic active hepatitis, cirrhosis and hepatocellular carcinoma in this area were 1.7%, 8.3%, 12.4%, 27 respectively. 6%, 38.1% and 20.7%, 56.4% of HCV-infected patients had the history of blood transfusion, blood donation and use of blood products. Prompt blood transmission is the main route of HCV infection in the area.The genotype distribution of HCV in this area is mainly type Ⅱ (77.4%). Followed by type Ⅲ (17.8%). And a small amount of Ⅱ Ⅲ mixed type (4.8%).