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目的观察短期胰岛素泵强化治疗对新诊断2型糖尿病患者血糖达标时间及3个月后复查糖基化血红蛋白的控制情况,从而改变糖尿病的临床进程。方法66例新诊断2型糖尿病患者随机分成两组,治疗组34例,给予2周时间胰岛素强化治疗后,改口服降糖药治疗;对照组32例给予直接口服药治疗,分别观察2组患者血糖达标时间及3个月后糖基化血红蛋白的控制情况。结果治疗组血糖达标达标时间为(2.5±0.8)d,对照组血糖达标时间为(7.5±1.6)d,2组数据比较差异有统计学意义(P<0.01)。3个月后糖基化血红蛋白情况,治疗组为(5.4±1.5)%,对照组为(6.3±1.8)%,2组数据对照差异有统计学意义(P<0.05)。结论新诊断2型糖尿病患者,经短期胰岛素泵强化治疗,能缩短血糖达标时间并维持长时间血糖的良好控制。
Objective To observe the short-term insulin pump intensive treatment of newly diagnosed type 2 diabetes patients with glycemic control time and 3 months after the review of glycosylated hemoglobin control, thus changing the clinical course of diabetes. Methods Sixty-six patients with newly diagnosed type 2 diabetes were randomly divided into two groups. The treatment group (34 cases) received insulin treatment for 2 weeks and then received oral hypoglycemic agents. The control group (32 cases) received oral treatment, and the patients in the two groups Glycemic control of glycemic hemoglobin after reaching the blood glucose standard time and 3 months later. Results The blood glucose reached the standard time (2.5 ± 0.8) d in the treatment group and (7.5 ± 1.6) days in the control group. The difference between the two groups was statistically significant (P <0.01). The glycosylated hemoglobin level after 3 months was (5.4 ± 1.5)% in the treatment group and (6.3 ± 1.8)% in the control group, with significant difference between the two groups (P <0.05). Conclusions Patients with newly diagnosed type 2 diabetes who underwent short-term intensive insulin pump therapy could shorten the blood glucose compliance time and maintain good long-term blood glucose control.