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目前已经证明每月肌肉注射乙酰苯基金属二羟孕酮(DHPA)150mg 和戊酸雌二醇(E2-EN)10mg 复合剂是一种高效避孕药,其临床副作用最小,而且很少影响子宫内膜出血。作者最近研究认为这个方案的一半剂量对抑制排卵是有效的。作者将受试者分为两组。她们为生育年龄,志愿参加的妇女,用每月一次避孕药前月经周期规则。Ⅰ组(7例)包括连续每月应用 DHPA/E2-EN,平均6.7年(最少3.6年,最多9.8年)。Ⅱ组为参加此试验前至少6个月没有用过激素避孕药。两组均采用深部臀肌注射 DHPA/E2-EN。长期使用者(Ⅰ组)在最后一次注射后25~30天之间注射,而对照的未
It has been demonstrated that a monthly intramuscular injection of acetophenone metal hydroxyprogesterone (DHPA) 150 mg and estradiol valerate (E2-EN) 10 mg complex is a highly effective contraceptive with minimal clinical side effects and rarely affects the uterus Endometrial bleeding. A recent study by the authors concluded that half the dose of this regimen is effective in suppressing ovulation. The authors divided the subjects into two groups. They are women of childbearing age, volunteer to participate in the monthly menstrual cycle contraceptive rules. Group I (7 cases) consisted of continuous monthly application of DHPA / E2-EN with an average of 6.7 years (minimum 3.6 years, maximum 9.8 years). Group II did not take any hormonal contraceptives for at least 6 months before participating in the trial. DHGP / E2-EN was injected into deep gluteal muscles in both groups. Long-term users (group I) were injected 25 to 30 days after the last injection, while controls