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目的探讨急诊应用胺碘酮治疗冠状动脉粥样硬化性心脏病(CHD)合并快速性心律失常患者的临床疗效。方法选取2015年6月至2016年6月于沈阳急救中心接受治疗的66例CHD合并快速性心律失常患者作为研究对象,将其随机分为对照组(33例)和观察组(33例),两组患者分别给予普罗帕酮和盐酸胺碘酮治疗。比较两组患者治疗效果、用药后心率改善值及不良反应发生情况。结果对照组和观察组治疗有效率分别为75.8%和93.9%,不良反应发生率分别为24.2%和6.1%,心率改善值分别为(44±8)次/min和(58±9)次/min,两组比较差异均有统计学意义(均P<0.05)。结论急诊采用胺碘酮治疗CHD合并快速性心律失常效果显著,具有较高安全性。
Objective To investigate the clinical efficacy of emergency amiodarone in the treatment of patients with coronary atherosclerotic heart disease (CHD) complicated with tachyarrhythmia. Methods Sixty-six patients with CHD complicated with tachyarrhythmia treated in Shenyang Emergency Center from June 2015 to June 2016 were selected as the research object and randomly divided into control group (33 cases) and observation group (33 cases) Two groups of patients were given propafenone and amiodarone hydrochloride treatment. The treatment effect, the improvement of heart rate and the incidence of adverse reactions after treatment were compared between the two groups. Results The effective rates of the control group and the observation group were 75.8% and 93.9% respectively, the rates of adverse reactions were 24.2% and 6.1% respectively, and the heart rate improvement values were 44 ± 8 and 58 ± 9 times / min, there was significant difference between the two groups (all P <0.05). Conclusion The effect of amiodarone in the treatment of CHD complicated with tachyarrhythmia in emergency department is significant and has high safety.