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胰十二指肠切除术是Whipple等人为治疗肝胰壶腹癌而首先提出,后来渐用于胰头癌、胆囊癌及十二指肠癌等疾病的治疗。过去,与该手术有关的发病率和死亡率都与吻合术式存在的问题有关。但是最新资料显示,运用胰管与空肠粘膜直接缝合的方法能显著降低胰空肠吻合术的发病率和死亡率。 病人与方法:在1980年1月至1997年3月间有300例病人(男185例、女115例,平均年龄64.9岁)在日本Toyan区中心医院做过胰十二指肠术,并包括行幽门保留的胰十二指肠切除
Pancreatoduodenectomy was first proposed by Whipple et al. for the treatment of hepato-ampullary carcinoma, and was later used for the treatment of pancreatic cancer, gallbladder cancer, and duodenal cancer. In the past, the morbidity and mortality associated with this procedure were related to the problems of anastomoses. However, the latest data show that the use of direct suturing of the pancreatic ducts and jejunum mucosa can significantly reduce the incidence and mortality of pancreaticojejunostomy. Patients and Methods: Between January 1980 and March 1997, 300 patients (185 males and 115 females, mean age 64.9 years) underwent pancreatoduodenectomy at the Central Hospital of Toyan District in Japan. Pyloric retained pancreatoduodenectomy