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本实验采用胸壁开窗术及显微录像电视系统,活体内观察了Wistar大鼠(n=60)在急性肺泡缺氧时(FiO_2=0.1,3min)肺表面微循环的变化。结果如下:急性肺泡缺氧时:①肺细动脉内径(ID)明显缩小,A_1组(ID≥60μm)平均减少18.00％,A_2组(40～59μm)减少15.10％,A3组(20～39μm)减少9.59％(与缺氧前比较p<0.001),肺细静脉内径(20～100μm)缩小12.43％(p<0.001),提示这两类肺微血管都有收缩,但细静脉收缩程度轻于细动脉;②
In this study, the changes of pulmonary surface microcirculation in Wistar rats (n = 60) under acute alveolar hypoxia (FiO 2 = 0.1, 3 min) were observed using the chest wall fenestration and microsurgical video system. The results were as follows: ① In the case of acute alveolar hypoxia: ① The ID of pulmonary arterioles was significantly reduced, with an average decrease of 18.00% in group A_1 (ID≥60μm), 15.10% in group A_2 (40 ~ 59μm), and group A3 (20 ~ 39μm) Decreased by 9.59% (p <0.001 compared with that before hypoxia), and the diameter of pulmonary arterioles (20 ~ 100μm) decreased by 12.43% (p <0.001), suggesting that both types of pulmonary microvasculature had constrictions, Arteries;