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声损伤对耳蜗毛细胞的影响是否与耳蜗血流供应障碍有关尚不十分清楚。应用硫酸卡那霉素(KM)作为示踪剂,用免疫组织学方法显示其含量,代表局部血流量。将豚鼠置于125dBSPL摇滚乐箱中暴露3小时,观察声暴露后5、30、60分钟及2、6、21小时耳蜗底转外侧壁的血流量变化。结果显示,声暴露后5～30分钟,血管纹毛细血管内几乎没有KM出现,而螺旋韧带血管内却有很多KM显示。螺旋器内也存在着KM;声暴露后60分钟,尽管
Whether the effect of acoustic damage on cochlear hair cells is associated with cochlear blood flow disorders is not well understood. Application of kanamycin sulfate (KM) as a tracer, immunohistochemistry showed its content, on behalf of the local blood flow. Guinea pigs were placed in 125dBSPL rock music box exposed for 3 hours to observe the sound exposure at 5,30,60 minutes and 2,6,21 hours after cochlear basal lateral wall of the blood flow changes. The results showed that there was almost no KM in capillary vessels within 5 to 30 minutes after sound exposure, while there were many KMs in the blood vessels of the spiral ligament. There are also KMs within the spiral; sound exposure for 60 minutes, though