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目的:研究肿瘤化疗相关性死亡的原因和预防方法。方法:回顾性总结10例肿瘤化疗相关性死亡的临床资料,分析化疗方案、化疗后存活时间、死亡原因和预防方法。结果:平均年龄63.0岁。4例使用含多西紫杉醇化疗方案;化疗后存活时间5~25 d,平均为14.5 d。结论:肿瘤化疗相关性死亡与患者既往病史、年龄和化疗药物等有关。对有肝肺肾病史、年龄>65岁的患者,避免使用含多西紫杉醇的化疗方案。
Objective: To study the causes and prevention of cancer-related chemotherapy-induced death. Methods: The clinical data of 10 patients with chemotherapy-related death from cancer were retrospectively analyzed. The chemotherapy regimen, the survival time after chemotherapy, the cause of death and the preventive measures were analyzed. Results: The average age was 63.0 years. Four patients received chemotherapy with docetaxel. The survival time after chemotherapy was 5 to 25 days, with an average of 14.5 days. Conclusion: Tumor chemotherapy-related deaths are related to past medical history, age and chemotherapeutic drugs. For patients with a history of hepatorenal disease, patients aged> 65 years, avoid docetaxel-containing chemotherapy regimens.