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利用1991年6月到1992年6月在石家庄等九个市、县的南北城乡研究现场采集到的婚检妇女血清标本,进行了355份20种血清游离氨基酸水平测定,结果显示:①牛磺酸、甘氨酸、丙氨酸、(?)氨酸、蛋氨酸、苯丙氨酸、γ—氨基丁酸、脯氨酸水平存在南北差异;⑦苏氨酸、谷氨酸、丙氨酸、胱氨酸、蛋氨酸、异亮氨酸、赖氨酸、脯氨酸水平存在城乡差异;③牛磺酸、苏氨酸、丝氨酸、甘氨酸、蛋氨酸、亮氨酸、苯丙氨酸、组氨酸、脯氨酸水平存在季节差异。结果提示某些血清游离氨基酸水平可能与神经管畸形的发生有关。
From June 1991 to June 1992 in Shijiazhuang and other nine cities and counties in the north and south urban and rural areas collected from the women of premarital women were tested 355 kinds of serum free amino acid levels were measured 355, the results showed that: ① taurine , Glycine, alanine, (?) - arginine, methionine, phenylalanine, γ-aminobutyric acid and proline; ⑦ threonine, glutamic acid, alanine, cystine , Methionine, isoleucine, lysine, proline levels exist between urban and rural areas; ③ taurine, threonine, serine, glycine, methionine, leucine, phenylalanine, histidine, proline There are seasonal differences in acid levels. The results suggest that some serum free amino acid levels may be related to the occurrence of neural tube defects.