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目的探讨保乳手术与改良根治术治疗Ⅰ、Ⅱ期乳腺癌的近期疗效。方法Ⅰ、Ⅱ期乳腺癌女性患者120例根据手术治疗方法的不同分为治疗组60例与对照组60例,治疗组采用保乳手术治疗,对照组采用改良根治手术。所有患者手术治疗结束后采用三维适形治疗计划。结果治疗组的手术时间、术中出血量、总引流量和腋窝淋巴结清扫时间明显少于对照组(P<0.05)。治疗组治疗后乳房美容优良率为90.0%,对照组为75.0%,组间比较,差异有统计学意义(P<0.05)。治疗组治疗后的生理状况、社会/家庭状况、情感状况和功能状况评分明显高于对照组,差异有统计学意义(P<0.05)。随访1年,治疗组的局部复发率与远处转移与对照组比较,差异无统计学意义(P>0.05)。结论相对于改良根治术,保乳手术治疗Ⅰ、Ⅱ期乳腺癌能减少创伤,提高乳房美容满意度,改善乳房功能,且安全性好,值得推广应用。
Objective To investigate the short-term curative effect of breast-conserving surgery and modified radical mastectomy on stage I and II breast cancer. Method Ⅰ, Ⅱ female 120 patients with breast cancer according to the different surgical treatment methods were divided into treatment group 60 cases and control group 60 cases, the treatment group was treated with breast-conserving surgery, the control group was modified radical mastectomy. All patients treated with 3D conformal treatment plan after surgery. Results The operation time, intraoperative blood loss, total drainage and axillary lymph node clearance time in the treatment group were significantly less than those in the control group (P <0.05). After treatment, the excellent and good rate of breast cosmetic treatment was 90.0% in the treatment group and 75.0% in the control group. There was significant difference between the two groups (P <0.05). After treatment, the physical condition, social status, family status, emotional status and functional status scores of the treatment group were significantly higher than those of the control group, with significant difference (P <0.05). After one year of follow-up, there was no significant difference in the local recurrence rate and distant metastasis between the treatment group and the control group (P> 0.05). Conclusion Compared with modified radical mastectomy, breast conserving surgery for stage Ⅰ and Ⅱ breast cancer can reduce trauma, improve breast cosmetic satisfaction, improve breast function, and good safety, it is worth popularizing and applying.