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目的:总结卵巢恶性肿瘤患者的临床特点及预后情况并探讨卵巢恶性肿瘤预后相关因素。方法:回顾性分析123例卵巢恶性肿瘤患者临床资料并进行随访,采用Kaplan-Meier法及cox多因素生存分析来分析预后影响因素。结果:123例卵巢恶性肿瘤患者中早期(I期+II期)73例,晚期(III期+IV期)50例;浆液性肿瘤60例,非浆液性肿瘤41例,非上皮性肿瘤22例;所有患者1、3、5年生存率分别为94%、77%、71%。多因素分析显示年龄、临床分期、组织学分级、淋巴结清扫情况是卵巢恶性肿瘤独立预后因素。结论:年龄、临床分期、组织学分级、淋巴结清扫情况是卵巢恶性肿瘤独立的预后因素,早期发现、早期诊断、合理治疗是提高患者生存率的关键。
Objective: To summarize the clinical characteristics and prognosis of patients with ovarian cancer and explore the prognostic factors of ovarian cancer. Methods: The clinical data of 123 patients with ovarian cancer were retrospectively analyzed and followed up. The Kaplan-Meier method and cox multivariate survival analysis were used to analyze the prognostic factors. Results: Of the 123 patients with ovarian malignancy, 73 were in the early stage (stage I + II) and 50 were in the advanced stage (stage III + IV). There were 60 serous tumors, 41 non-serous tumors and 22 non-epithelial tumors The 1, 3, 5-year survival rates of all patients were 94%, 77% and 71%, respectively. Multivariate analysis showed that age, clinical stage, histological grade, lymph node dissection were independent prognostic factors of ovarian cancer. Conclusion: Age, clinical stage, histological grade and lymph node dissection are independent prognostic factors of ovarian cancer. Early detection, early diagnosis and reasonable treatment are the keys to improve patient survival rate.