2010—2014年南宁市手足口病流行病学特征

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目的分析近年南宁市手足口病(HFMD)分布特点和流行趋势,为制定HFMD防制对策提供依据。方法从《国家疾病监测信息报告管理系统》和《突发公共卫生事件报告管理信息系统》分别收集2010—2014年7月南宁市报告的HFMD病例资料和暴发及聚集性疫情的现场调查资料,用描述流行病学方法进行分析。结果 2010—2014年7月南宁市共报告HFMD 230 874例,重症2 042例,死亡76例。为5岁及以下儿童发病221 617例,发病率为8 280/10万,占发病总数的95.99%。全年各月份均有病例出现,发病高峰在4—7月,其病例数占总病例数的62.38%,职业以散居和幼托儿童为主,分别占总病例数的70.97%和26.32%。实验室诊断3 144例,其中肠道病毒71(EV71)型占44.27%,柯萨奇病毒A16(Cox A16)型占24.49%;HFMD死亡儿童感染的病毒主要为EV71型,占死亡总数的82.89%。近5年来,南宁市发生5例以上的聚集性HFMD疫情50起,其中49起发生在托幼机构。结论南宁市HFMD发病呈逐年上升趋势,隔年出现以EV71型为主的流行,重症和死亡病例也增多,对此应加强研究5岁以下儿童的防治。 Objective To analyze the distribution characteristics and epidemic trend of HFMD in Nanning in recent years and provide the basis for making HFMD prevention and control measures. Methods The data of HFMD cases reported in Nanning City from July 2010 to July 2014 and the field survey data of outbreak and cluster epidemic situation were collected respectively from the National Disease Surveillance Information Reporting Management System and the Public Health Emergencies Reporting Management Information System. Describe the epidemiological method for analysis. Results From July 2010 to July 2014, a total of 874 cases of HFMD 230 were reported in Nanning City, with severe cases of 2 042 cases and 76 deaths. 221 617 cases of children aged 5 years and under were diagnosed with a prevalence of 8 280/10 million, accounting for 95.99% of the total. Cases occurred in all months of the year with the peak incidence in April-July, accounting for 62.38% of the total number of cases. The majority of occupations were diaspora and childcare children, accounting for 70.97% and 26.32% of the total cases respectively. The laboratory diagnosis of 3 144 cases, of which enterovirus 71 (EV71) accounted for 44.27%, Cox A16 (Cox A16) accounted for 24.49%; HFMD death of children infected with the virus is mainly EV71 type, accounting for 82.89 deaths %. In the past five years, there were 50 outbreaks of HFMD accumulating in more than 5 cases in Nanning City, of which 49 occurred in nurseries. Conclusions The incidence of HFMD in Nanning is increasing year by year. The epidemic, severe cases and fatal cases with EV71 mainly occur every other year also increase. Therefore, the prevention and treatment of children under 5 years of age should be strengthened.
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