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目的:探讨应变率成像技术评价左冠状动脉起源异常患儿局部心肌功能的临床应用价值。方法:应用应变率成像技术比较16例左冠状动脉起源于肺动脉(Anomalous origin of the left coronary artery from the pulmonary artery,LCAPA)患儿与39例正常儿童左心室不同心肌节段的应变率值以及应变值。结果:对照组平均收缩期峰值应变率(-2.12±0.75)s-1,收缩期应变(-25.24±4.07)%,舒张早期应变率(2.32±0.69)s-1,舒张晚期应变率(1.65±0.61)s-1;病例组平均收缩期峰值应变率(-1.42±0.49)s-1,收缩期应变(-17.56±5.71)%,舒张早期应变率(1.48±0.49)s-1,舒张晚期应变率(0.85±0.42)s-1。病例组收缩期及舒张期应变率及应变均小于对照组,差异有显著意义(P<0.01)。病例组室间隔基底段的应变率值及应变值与其它节段相比较差异有显著意义。病例组基底段收缩期峰值应变率(-2.22±.41)s-1,收缩期应变(-25.24±4.07)%,舒张早期应变率(2.32±0.69)s-1,舒张晚期应变率(1.65±0.61)s-1。结论:应变率成像技术可以评价左冠状动脉起源于肺动脉患者局部心肌功能。
Objective: To investigate the clinical value of strain rate imaging in assessing regional myocardial function in children with abnormal origins of left coronary artery. Methods: Strain rate and strain of 16 different cardiac segments of left ventricular origin in the left coronary artery from the pulmonary artery (LCAPA) and 39 normal children were compared using strain rate imaging. value. Results: The mean systolic peak strain rate (-2.12 ± 0.75) s-1, systolic strain (-25.24 ± 4.07)%, early diastolic strain rate (2.32 ± 0.69) s-1 and late diastolic strain rate (1.65 ± 0.61) s-1. The average systolic peak strain rate (-1.42 ± 0.49) s-1, systolic strain (-17.56 ± 5.71)% and early diastolic strain rate (1.48 ± 0.49) s- Late strain rate (0.85 ± 0.42) s-1. The systolic and diastolic strain rate and strain in case group were less than those in control group, with significant difference (P <0.01). The incidence of strain rate and strain in the basal segment of interventricular septum were significantly different from those in other segments. The peak systolic strain rate (-2.22 ± 41) s-1, systolic strain (-25.24 ± 4.07)%, early diastolic strain rate (2.32 ± 0.69) s-1 and late diastolic strain rate (1.65 ± 0.61) s-1. CONCLUSIONS: Strain rate imaging can assess local myocardial function in patients with left coronary artery originating from pulmonary arteries.