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应用抗HLA-DR单克隆抗体,对6例死于各种疾病患者的正常鼓膜表皮进行免疫组织化学观察。结果示:正常鼓膜表皮内有树突状细胞(DC)分布。提示胆脂瘤基质内之朗罕细胞可能为鼓膜表皮内DC移入所致。
Immunohistochemistry was performed on 6 cases of normal eardrum tympanites who died of various diseases using anti-HLA-DR monoclonal antibody. The results showed that: normal eardrum dendritic cells (DC) distribution. It is suggested that Langerhans cells in cholesteatoma may be induced by DC in the tympanic membrane.