论文部分内容阅读
目的比较β－七叶皂甙钠和甘露醇及地塞米松治疗放射性脑水肿的疗效。方法４９例经头颅ＣＴ或（和）ＭＲＩ证实的放射性脑水肿随机分为甘露醇对照组［１１例，１ｇ／（ｋｇ·ｄ）］、地塞米松对照组（１１例，２０ｍｇ／ｄ）、单纯β－七叶皂甙钠治疗组（１４例）和β－七叶皂甙钠并用甘露醇组（１３例）。后２组均采用β－七叶皂甙钠２０ｍｇ溶于２５０ｍＬ生理盐水中静滴。结果单纯β－七叶皂甙钠治疗组有效比例为１３／１４，２个β－七叶皂甙钠治疗组总有效比例为２６／２７，明显高于甘露醇组（７／１１）和单纯地塞米松（８／１）组。结论β－七叶皂甙钠治疗放射性脑水肿有效，且优于甘露醇和地塞米松，与甘露醇合用疗效更佳
Objective To compare the therapeutic effect of β-aescinate and mannitol and dexamethasone on radiation-induced brain edema. Methods 49 cases of radioactive brain edema confirmed by skull CT or (and) MRI were randomly divided into mannitol control group (11 cases, 1g / (kg · d)], dexamethasone control group (11 cases, 20mg / d) Simple β-aescinate treatment group (14 cases) and β-aescinate sodium and mannitol group (13 cases). After 2 groups were used β-aescinate 20mg dissolved in 250mL saline intravenous infusion. Results The effective ratio of simple β-aescinate treatment group was 13/14, and the total effective ratio of two β-aescinate treatment groups was 26/27, which was significantly higher than that of mannitol group (7/11) Meson (8/1) group. Conclusion β-aescinate treatment of radiation-induced brain edema, and better than mannitol and dexamethasone, combined with mannitol better efficacy