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近来认为,溶血性尿毒综合征(简称HUS)与产生毒素的大肠杆菌有关系,而这种毒素又与志贺氏毒素有关。这种与HUS有关的大肠杆菌或者产生一种与志贺氏毒素基本相同的毒素,即志贺氏痢疾杆菌血清型Ⅰ型的外毒素;或者产生一种虽在免疫学上没有联系,但在结构与功能上与志贺氏毒素密切相关的毒素,这种毒素称之为类志贺氏毒素Ⅰ型(SLT-Ⅰ或梅毒毒素Ⅰ);与之相关不密切,不被志贺氏毒素抗体中和的那种毒素称为类志贺氏毒素Ⅱ(SLT-Ⅱ或梅毒毒素Ⅱ)。已知产生类志贺氏毒素Ⅰ型及/或Ⅱ型最常见的大肠杆菌是大肠杆菌
Recently, hemolytic uremic syndrome (referred to as HUS) and toxin-producing Escherichia coli, and this toxin and Shiga toxin-related. This HUS-associated Escherichia coli produces either a toxin that is essentially the same as Shiga toxin, ie, an exotoxin of Shigella dysenteriae serotype I, or a species that, although not immunologically linked, Structure and function of shiga toxin closely related to toxins, this toxin called Shiga toxin type Ⅰ (SLT-Ⅰ or syphilis toxin Ⅰ); is not closely related with, not Shiga toxin antibodies The type of toxin that is neutralized is called Shiga toxin II (SLT-II or syphilis toxin II). The most common E. coli known to produce Shigella spp. Type I and / or type II is Escherichia coli