脑梗死与高同型半胱氨酸的相关性研究

• 作 者: 杨富珍 周雄俊 宋继东
• 机 构: 河南省温县人民医院神经内科,
• 出 处: 中国实用医药
• 发表日期: 2013年27期
• 关键词: 检测指标 观察组 缺血性脑卒中 脑血管病 统计学方法 临床资料 高胱氨酸 空腹采血 前驱症状 内膜中层厚度

目的分析脑梗死与高同型半胱氨酸的相关性。方法选取本院于2010年2月至2012年12月收治的80例脑梗死患者作为观察组,另选80例健康人群为对照组,采取血浆测定两组的同型半胱氨酸水平、叶酸等指标,并进行比较分析。结果观察组患者血浆高同型半胱氨酸水平明显高于对照组,比较差异有统计学意义(P<0.01),不同性别的患者高同型半胱氨酸水平差异有统计学意义(P<0.05)。结论脑梗死的发生与高同型半胱氨酸水平有密切的相关性,叶酸和维生素B12的变化影响着高同型半胱氨酸水平。

Objective To analyze the correlation between cerebral infarction and homocysteine. Methods Eighty patients with cerebral infarction who were treated in our hospital from February 2010 to December 2012 were selected as the observation group and another 80 healthy people as the control group. Plasma homocysteine ​​level, folic acid, Indicators, and comparative analysis. Results The plasma levels of homocysteine ​​in the observation group were significantly higher than those in the control group (P <0.01), and there was significant difference in the homocysteine ​​levels between different sex groups (P <0.05 ). Conclusions The occurrence of cerebral infarction is closely related to the level of homocysteine. The changes of folic acid and vitamin B12 affect the level of homocysteine.