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目的 探讨早期胃癌的诊断、治疗方法和影响预后的因素。方法 对1981 年5 月至1995 年5 月收治的50 例早期胃癌的临床资料进行回顾性分析。结果 胃造影和纤维胃镜诊断率分别为85 .7 % (24/28) 及98 .0 % (49/50) ,行D1 + No7 手术者27例,规范性D2 者22 例,近残胃切除者1 例。瘤体为单病灶者48 例,多病灶者2 例,肿瘤位于粘膜内者19 例(38 .0 % ) ,侵至粘膜下层者31 例。除5 例有淋巴结转移或瘤栓(10 .0 % ) 外,余45 例均为阴性,而病灶小于2 cm 的19 例患者均无淋巴转移。48 例得到随访,中位随访时间为6 年8 个月,2 例有淋巴结转移者在随诊期间死亡。全组无1 例局部复发,其总的5 年、10 年生存率分别为97 .8 % 和92 .1 % 。结论 早期胃癌的诊断应以胃造影和纤维胃镜检查相结合的方法,对病灶直径小于2 cm 者施行扩清术应持慎重态度,淋巴结转移是影响预后的惟一因素,而年龄、病灶大小、病理类型及手术方式等对预后均没有明显影响。
Objective To investigate the diagnosis, treatment and prognostic factors of early gastric cancer. Methods The clinical data of 50 cases of early gastric cancer admitted to our hospital from May 1981 to May 1995 were analyzed retrospectively. Results Gastric angiography and fiber endoscopy diagnostic rates were 85. 7% (24/28) and 98%. 0% (49/50), line D1 + No7 operation in 27 cases, normative D2 in 22 cases, nearly residual gastrectomy in 1 case. 48 cases of single tumor lesions, multiple lesions in 2 cases, tumor in the mucosa in 19 cases (38.0%), invaded the submucosa in 31 cases. Except 5 cases with lymph node metastasis or tumor suppository (10 .0%), more than 45 cases were negative, while the lesion less than 2 cm in 19 patients without lymph node metastasis. Forty-eight patients were followed up for a median follow-up of 6 years and 8 months. Two patients with lymph node metastasis died during follow-up. The whole group without local recurrence in 1 case, the total 5-year, 10-year survival rates were 97. 8% and 92. 1%. Conclusion The diagnosis of early gastric cancer should be combined with gastric angiography and gastroscopy, the diameter of lesions less than 2 cm in patients with dissection should be taken cautious attitude, lymph node metastasis is the only prognostic factor, but the age, lesion size, pathology Type and surgical methods have no significant effect on prognosis.