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报道经蝶显微手术治疗垂体腺瘤362例,均经CT扫描或MRI确诊。其中大腺瘤145例(40.1%),微腺瘤217例(59.9%)。手术采取经唇下-鼻中隔-蝶窦入路或经鼻前庭-鼻中隔-蝶窦入路两种方式行肿瘤切除术。术后无死亡。296例行随访观察,随访期6月至7.5年(平均3.5年),246例(83.1%)恢复良好,50例(16.9%)肿瘤有复发,需行再次手术,或采用药物、放疗或放射外科治疗。文中对经蝶手术治疗的原则与术式进行了讨论。
Reports of 362 cases of pituitary adenoma treated with transsphenoidal microsurgery were confirmed by CT scan or MRI. Among them, 145 (40.1%) had macroadenomas and 217 (59.9%) had microadenomas. The operation was performed by submucosal-nasal septum-sphenoid sinus approach or nasal vestibular-nasal septum-sphenoid sinus approach. No deaths after surgery. 296 routine follow-up observations, follow-up period from June to 7.5 years (average 3.5 years), 246 cases (83.1%) recovered well, 50 cases (16.9%) tumor recurrence, need reoperation, or use of drugs, radiotherapy or radiation Surgical treatment. In this paper, the principles and surgical methods of transsphenoidal surgery are discussed.