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癫癇连续状态的死亡率颇高,現有药物治疗尚不太意滿。作者参照Berrhard和Bohm二氏及其他学者动物实驗結果和临床观察,以2% xylocaine(进口货,即利多卡因)靜脉注射治疗10例癫癇连续状态,剂量約为每公斤1～6毫克,每分钟注射20毫克,必要时可于20～30分钟重复注射,或将剂量加大。疗效方面,只注射xylocaine而能迅速控制搐搦者7例,事先注射苯巴比妥鈉0.1～0.3克无效再注射xylocaine即能控制搐搦者5例,注射xylocaine一次无效,再注射苯巴比妥0.3克即能控制搐搦者1例,注射苯巴比妥及xylocaine各一次无效而需併用他药(三聚乙醛或阿米妥鈉)者3例。根据初步分析目前尚不能确定有效剂量,因所用剂量同患者的年龄、体重、病因、癫癇连续状态的严重程度、疗效似无一定的关系。除了xylocaine多能迅速控制癫癇连续状态以外,9名患者在注射两小时
The status of epilepsy continuous high mortality, the existing drug treatment is not too full. The authors refer to Berrhard and Bohm II and other scholars animal experimental results and clinical observations, with 2% xylocaine (imported goods, lidocaine) intravenous treatment of 10 cases of epilepsy continuous state, the dose of about 1 to 6 mg per kg, each Minute injection of 20 mg, if necessary, in 20 to 30 minutes repeated injections, or increase the dose. Efficacy, only the injection of xylocaine and can quickly control convulsions in 7 cases, prior injection of phenobarbital 0.1 to 0.3 grams of invalid injection of xylocaine that can control convulsions in 5 cases, injection of xylocaine once invalid, and then injected with phenobarbital 0.3 In one case, convulsions were controlled in 3 cases, and phenobarbital and xylocaine were ineffective in 3 cases. According to the preliminary analysis, the effective dose can not be determined at present because the dose used may not be related to the patient’s age, weight, etiology, the severity of the continuous state of epilepsy and the efficacy. In addition to xylocaine can quickly control the continuous status of epilepsy, nine patients were injected for two hours