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无脉络膜症是一种罕见的X连锁隐性遗传病。通常表现为进行性夜盲,视野收缩,40-50岁全盲。女性携带者一般无明显症状,但眼底镜可检出眼底的椒盐状或斑驳状病变。目前该病的生化基础和分子机制尚不完全被人们了解,逆向遗传学将为我们找到打开迷宫大门的钥匙。1985年Nussbaum首次将TCD基因定位于X_(q1.3-
Choroidal disease is a rare X-linked recessive genetic disease. Usually manifested as progressive night blindness, visual field contraction, 40-50-year-old blind. Female carriers generally no obvious symptoms, but the ophthalmoscope can detect the saltpest or mottled retinal lesions. At present, the biochemical basis and molecular mechanism of the disease are not yet fully understood, reverse genetics will find the key to open the door to the maze. In 1985, Nussbaum first mapped the TCD gene to X_ (q1.3-