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目的:探讨妊娠期肝内胆汁淤积症对于新生儿的影响。方法选择2010年1月~2014年12月在我院住院治疗的妊娠期肝内胆汁淤积症孕妇120例作为观察组,同期选择在我院进行建档分娩的孕妇120例作为对照组,观察两组孕妇与新生儿的预后。结果两组都顺利分娩,产妇与新生儿都存活;观察组产后出血和妊娠期高血压疾病的发病率都明显高于对照组(<0.05),且新生儿窒息、剖宫产和早产的发病率也明显高于对照组(<0.05)。结论妊娠期肝内胆汁淤积症使得新生儿有不良预后,可使早产与新生儿窒息发生率增加,要积极加强干预,从而改善母婴结局。“,”Objective To discuss the ef ect of intrahepatic cholestasis in pregnancy on neonatal. Methods 120 cases of pregnant women with intrahepatic cholestasis in pregnancy from January 2010 to December 2014 in our hospital as observation group, 120 cases with document delivery as control group, to observe the prognosis of pregnant women and neonates between two groups. Results Patients of two groups had a smooth delivery,maternal and neonatal al survived. Postpartum hemor hage and incidence of gestational hypertension disease were significantly higher than that control group ( <0.05). Neonatal asphyxia,caesarean section and incidence of premature were significantly higher than that control group ( <0.05). Conclusion Intrahepatic cholestasis in pregnancy can make newborn bad prognosis, increase asphyxia incidence of preterm birth and neonatal, it need to strengthen the intervention,so as to improve maternal and neonatal outcomes.