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小鼠静脉注射氯化钙可抑制醋酸所致扭体反应,也提高小鼠对热刺激的痛阈值,证明钙有镇痛作用。但并不提高小鼠对电刺激的痛阈。异搏定则对上述三种致痛作用均无对抗。
Intravenous injection of calcium chloride in mice inhibited the acetic acid-induced writhing response, and also increased the thermal stimulus pain threshold in mice, demonstrating that calcium has analgesic effects. However, it does not increase the pain threshold for electrical stimulation in mice. Verapamil has no resistance to the above three kinds of pain.