Activation of JNK by TPA promotes apoptosis via PKC path way in gastric cancer cells

• 作 者: YanChen QiaoWu Si-YangSong Wen
• 机 构: KeyLaboratoryoftheMinistryofEducationforCellBiologyandTumorCellEngineering
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2002年6期
• 关键词: JNK 激活 TPA 胃癌细胞凋亡 PKC通路 促进作用
• 基金项目: 国家杰出青年科学基金，国家自然科学基金，福建省自然科学基金

AIM: JNK cascade plays an important role in cell proliferation, differentiation and apoptosis. However, the exact function of JNK cascade for apoptosis induction remains largely unknown. In this study, the role of JNK activation stimulated by TPA in the p