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目的探讨多巴胺联合硝普钠治疗心力衰竭的临床疗效。方法选取保定市第五医院2013年7月—2016年7月收治的心力衰竭患者80例,根据随机数字表法分为对照组(n=40)和观察组(n=40)。对照组患者给予常规治疗,观察组患者给予多巴胺联合硝普钠治疗。比较两组患者的临床疗效及治疗前后心功能指标[心胸比、左心室射血分数(LVEF)、左心室舒张末期内径(LVD)、左心室短轴缩短率(LVFS)]。结果观察组患者临床疗效优于对照组(P<0.05)。治疗前,两组患者心胸比、LVEF、LVD、LVFS比较,差异无统计学意义(P>0.05);治疗后,观察组患者心胸比、LVD低于对照组,LVEF、LVFS高于对照组(P<0.05)。结论多巴胺联合硝普钠治疗心力衰竭临床疗效确切,可有效改善患者临床症状,改善心功能。
Objective To investigate the clinical efficacy of dopamine combined with sodium nitroprusside in the treatment of heart failure. Methods Eighty patients with heart failure admitted to the Fifth Hospital of Baoding from July 2013 to July 2016 were divided into control group (n = 40) and observation group (n = 40) according to random number table. Patients in the control group were given routine treatment, and patients in the observation group were treated with dopamine and sodium nitroprusside. The clinical efficacy and cardiac function before and after treatment were compared between the two groups [cardiac thoracic ratio, left ventricular ejection fraction (LVEF), left ventricular end diastolic dimension (LVD), left ventricular fractional shortening (LVFS)]. Results The clinical efficacy of the observation group was better than that of the control group (P <0.05). Before treatment, there was no significant difference in cardiothoracic ratio, LVEF, LVD and LVFS between the two groups (P> 0.05); after treatment, the cardiothoracic ratio, LVD in the observation group were lower than those in the control group, LVEF and LVFS were higher than those in the control group P <0.05). Conclusions Dopamine combined with sodium nitroprusside is effective in treating heart failure. It can effectively improve clinical symptoms and improve cardiac function.