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目的探讨临床药师参与重症监护室(ICU)与呼吸科抗菌药物合理应用实践。方法按照《全国抗菌药物临床应用专项整治活动方案》要求,江苏省南通大学附属医院加强对抗菌药物合理应用的管理,临床药师通过参与ICU与呼吸科抗菌药物的管理与药学实践,利用本院药学部合理用药系统软件统计分析江苏省南通大学附属医院2013—2014年ICU与呼吸科住院患者抗菌药物使用率、使用强度及微生物样本送检率,进一步监测临床抗菌药物的应用。结果 ICU住院患者抗菌药物使用率由2013年的92.22%下降到2014年的83.58%;呼吸科住院患者抗菌药物使用率由2013年的72.86%下降到2014年的64.61%。ICU住院患者抗菌药物使用强度由2013年的232.35%下降到2014年的180.06%,呼吸科住院患者抗菌药物使用强度由2013年的158.82%下降到2014年的134.50%。ICU住院患者微生物检验样本送检率由2013年的59.81%上升为2014年的180.06%,呼吸科住院患者微生物检验样本送检率由2013年的44.41%上升为2014年的77.43%。结论临床药师通过参与ICU与呼吸科抗菌药物的管理与药学实践,可进一步促进临床重点科室抗菌药物的合理应用,保证患者药物治疗效果及用药安全。
Objective To explore the rational application of clinical pharmacists in the intensive care unit (ICU) and respiratory medicine antibacterials. Methods In accordance with the requirements of the National Program of Special Rectification of Antibiotics for Clinical Applications, Nantong University Affiliated Hospital of Jiangsu Province strengthened the management of the rational use of antimicrobial agents. By participating in the management and pharmacy practice of ICU and respiratory antibacterials, clinical pharmacists used the pharmacy Department of rational use of drug system software statistical analysis of Jiangsu Nantong University Hospital 2013-2014 ICU and inpatient inpatient antibiotic use rate, intensity of use and delivery rate of microbial samples to further monitor the clinical application of antibacterial drugs. Results The inpatient antibiotic use rate in ICU dropped from 92.22% in 2013 to 83.58% in 2014; the inpatient use of antibiotics dropped from 72.86% in 2013 to 64.61% in 2014. The intensity of antimicrobial use in inpatients in ICU dropped from 232.35% in 2013 to 180.06% in 2014, and the intensity of antibacterial use in residency patients decreased from 158.82% in 2013 to 134.50% in 2014. The ICU inpatient microbiological test sample submission rate increased from 59.81% in 2013 to 180.06% in 2014, while the inpatient respiratory microbiology sample rate increased from 44.41% in 2013 to 77.43% in 2014. Conclusion The clinical pharmacists can further promote the rational use of antimicrobial agents in key clinical departments by participating in the management and pharmacy practice of ICU and respiratory department antibacterials to ensure the therapeutic effect and medication safety of patients.