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作者选择100例体重20kg以下,体质良好的小儿(1～6岁),随机分成四组。6个月以内的小儿不用氟烷。NH组(n=24)不用术前药。吸氟烷诱导;NI组(n=25)不用术前药吸异氟醚诱导;TH组(n=27)和TI组(n=24)吸氟烷或异氟醚诱导前30min,经直肠分别灌入40％硫喷妥钠30mg kg~(-1)。全部患儿均用脉搏氧饱和度计监测。诱导时还伍用60％N_2O—O_2。四组患儿的体重和性别分配均相仿。凡给术前药的患儿均嗜睡或入睡,而未用术前药者虽平静、合作但均未入睡有些哭闹(P<0.005),术前用药患儿的SaO_2均低于未用术前药者(P<0.05),NI组的氧饱和度最低,(P<0.005),其它3组间的最低SaO_2却无明显差异。
The author chose 100 cases weighing 20kg or less, good physical children (1 ~ 6 years old) were randomly divided into four groups. Children within 6 months do not need halothane. NH group (n = 24) without preoperative drugs. (N = 25) were not induced by isoflurane preoperatively in the NI group; those in the TH group (n = 27) and the TI group (n = 24) The rats were infused with 40% thiopental 30 mg kg ~ (-1) respectively. All children were monitored with pulse oximeter. Induction also with 60% N_2O-O_2. Four groups of children’s weight and gender distribution are similar. Children who were given premedication had drowsiness or asleep, while those who did not use preoperative medication were both crying (P <0.005), although they did not fall asleep when co-operating with the preoperative medication (P <0.05). The oxygen saturation in NI group was the lowest (P <0.005), but there was no significant difference among the other three groups.