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目的:了解食管癌高发区贲门癌的发病情况,制定更为有效的防治策略。方法:在食管癌高发区应用电子内镜直接碘染色检查法对高危人群共行3次内镜普查。结果:1)贲门癌的癌前病变即贲门腺上皮重度不典型增生的检出率为0.62%～1.50%。2)早期贲门癌的检出率分别为0.44%、0.68%及0.64%。中晚期贲门癌检出率分别为0.22%、0.17%及0.21%。3)91.30%～95.00%贲门重度不典型增生及早期贲门癌病变位于贲门时钟位(顺时针)10点位～2点位。大多数贲门癌前病变及早期贲门癌内镜下主要表现为贲门粘膜糜烂或浅溃疡。4)食管癌与贲门癌检出率之比为2.4～4.1:1。结论:在食管癌高发区直接应用内镜进行普查,除对食管癌及其癌前病变有较高的检出率外,对贲门癌及其癌前病变也有较高的检出率,因此在食管癌高发区也应重视贲门癌的防治及研究工作。
Objective: To understand the incidence of esophageal cancer in the high incidence of cardia cancer, to develop a more effective prevention and treatment strategies. Methods: In the high incidence of esophageal cancer using electronic endoscopic direct iodine staining test for high-risk groups co-line 3 endoscopic screening. Results: 1) The detection rate of cardial glandular epithelial dysplasia in precancerous lesions was 0.62% ~ 1.50%. 2) The detection rates of early cardia cancer were 0.44%, 0.68% and 0.64% respectively. The detection rate of middle and late cardia cancer was 0.22%, 0.17% and 0.21% respectively. 3) 91.30% ~ 95.00% Cardia severe dysplasia and early gastric cardia lesions located in the cardia clock (clockwise) 10 points to 2 points. Most of cardial precancerous lesions and early gastric cardia endoscopy mainly for gastric mucosal erosion or shallow ulcer. 4) The detection rate of esophageal and cardia cancer ratio of 2.4 to 4.1: 1. Conclusion: In the high risk area of esophageal cancer, direct application of endoscopy for census, in addition to esophageal cancer and precancerous lesions have a higher detection rate, the cardia cancer and precancerous lesions also have a higher detection rate, so in High incidence of esophageal cancer should pay attention to the prevention and treatment of cardiac cancer research.