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从桑白皮中分离出许多酚性成分,并研究了其结构和药理活性。但关于其叶的成分及其药理活性的研究报告很少。本文研究了桑(Morus alba)叶中4种主要黄酮醇甙的分离和鉴定及这些黄酮醇甙对葡糖转移酶催化的粘着性水溶性葡聚糖合成的抑制作用,这对于预防龋齿有用。从桑叶提取物中分离出4种黄酮醇甙类(1～4)。这些化合物均为FeCl_3反应和Mg—HCl试验阳性。酸水解
A number of phenolic compounds were isolated from Morus alba, and their structure and pharmacological activities were studied. However, there are few studies on the composition of its leaves and their pharmacological activities. This paper studied the isolation and identification of four main flavonol glycosides in Morus alba leaves and the inhibitory effect of these flavonol glycosides on the glucosyltransferase-catalyzed, adhesive water-soluble glucan synthesis, which is useful for the prevention of dental caries. Four flavonol steroids (1 to 4) were isolated from the mulberry leaf extract. These compounds are all positive for the FeCl_3 reaction and the Mg-HCl test. Acid hydrolysis