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目的:分析患者使用乙胺吡嗪利福异烟片Ⅱ出现不良反应的可能药物及解决方案。方法:临床药师通过查阅文献并结合患者病情,分析导致患者出现不良反应的可能抗结核药物。结果:引起患者出现全身皮疹不良反应的抗结核药物可能为乙胺丁醇,治疗方案为将利福平改为利福喷丁联合异烟肼、吡嗪酰胺抗结核治疗。结论:临床药师参与临床治疗可促进用药合理化,保证患者用药安全。
OBJECTIVE: To analyze possible drugs and solutions for adverse reactions of ethylamine pyrimethamine and isoprenone II in patients. Methods: The clinical pharmacist reviewed the literature and combined with the patient’s condition to analyze possible anti-TB drugs that cause adverse reactions in patients. Results: The anti-tuberculosis drugs that caused adverse systemic rashes may be ethambutol. The treatment regimen changed rifampicin to rifapentine combined with isoniazid and pyrazinamide antituberculous therapy. Conclusion: The participation of clinical pharmacists in clinical treatment can promote the rationalization of medication and ensure the safety of patients.