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目的了解2009—2015年桐乡市人间布鲁氏菌病(布病)流行情况,为制定防治策略提供依据。方法采用虎红凝集试验和试管凝集试验对主动监测的从事牛羊养殖、交易、屠宰和畜产品加工等职业人群及出现可疑布病相关症状的被动监测人员进行布病血清学检测。血清学阳性者采血接种双相血培养瓶增菌培养,并进行布鲁氏菌种型鉴定,分析布病流行趋势和分布特征。结果 2009—2015年桐乡市共监测1 562人,血清学阳性52例,阳性率为3.33%,血清阳性率呈上升趋势(P=0.01),职业人群发病以牲畜屠宰、运输交易人员最高,阳性率分别为4.55%和4.10%,不同职业人群感染率差异有统计学意义(P<0.01);发病时间以1—6月为主,感染人群和感染方式呈多样化。结论桐乡市应加强畜间检疫和管理,改变不良操作行为;加强大众健康教育,切实提高自我保护意识和防病能力。
Objective To understand the epidemic situation of human brucellosis (cloth brucellosis) in Tongxiang City from 2009 to 2015, and to provide the basis for making prevention and treatment strategies. Methods Serum tests of brucellosis were carried out on occupational groups, such as cattle and sheep breeding, trading, slaughtering and processing of livestock products, and passive monitoring personnel with symptoms related to suspicious brucellosis, which were actively monitored by tiger agglutination test and test tube agglutination test. Seropositive positive blood donation biphasic blood culture flask enrichment culture, and Brucella species identification, analysis of brucellosis epidemic trends and distribution characteristics. Results A total of 1 562 seropositive patients were detected in Tongxiang City from 2009 to 2015, with a positive rate of 3.33%. The positive rate of seroprevalence was on the rise (P = 0.01). The incidence of occupational diseases was highest in livestock slaughter and transport traders, Rates were 4.55% and 4.10%, respectively. The infection rates among different occupational groups were significantly different (P <0.01). The onset time was mainly from January to June, and the infection pattern and infection pattern were diversified. Conclusion Tongxiang City should strengthen quarantine and management of animal husbandry and change bad behavior. Strengthen public health education and effectively improve self-protection awareness and disease prevention.