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目的探讨超敏CRP(hsCRP)检测在新生儿败血症中的临床意义。方法 2009年7月至2011年7月我院NICU收治的临床诊断新生儿败血症的78例患儿作为观察组,入院时和恢复期检测静脉血hsCRP,并与对照组(60例正常新生儿)作比较。结果观察组疾病初期血hsCRP及其阳性率明显高于对照组,恢复期hsCRP降至正常或接近正常,比较差异有统计学意义(P<0.05)。结论 hsCRP检测对新生儿败血症的诊断和疗效监测有重要意义,特异性和敏感性高,结果准确可靠,值得推广。
Objective To investigate the clinical significance of hsCRP detection in neonatal sepsis. Methods From July 2009 to July 2011, 78 children with clinical diagnosis of neonatal sepsis admitted to NICU of our hospital were selected as the observation group. Venous blood hsCRP was measured at admission and during convalescence. Compared with the control group (60 normal newborns) compared to. Results The hsCRP and its positive rate in the early stage of the disease in the observation group were significantly higher than those in the control group. The hsCRP in the recovery period was reduced to normal or nearly normal, with statistical significance (P <0.05). Conclusion hsCRP detection of neonatal sepsis diagnosis and efficacy monitoring of great significance, specificity and sensitivity, the results are accurate and reliable, it is worth promoting.