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硝酸甘油治疗心绞痛已有100余年历史,但其作用短暂常须频繁用药,对患者不便,尤在夜间干扰睡眠。近来国内有应用长效硝酸甘油制剂的报道,但药品作用仅维持10小时左右。1983年起我们使用武汉市医学科学研究所研制的硝酸甘油透皮贴敷剂治疗冠心病心绞痛157例,结果如下.
Nitroglycerin has been used in the treatment of angina for more than 100 years. However, its short-acting effects often require frequent medication, which is inconvenient for patients and especially sleeps at night. Recently there are reports of the application of long-acting nitroglycerin preparations, but the drug effect is only maintained for about 10 hours. Since 1983, we use the Wuhan Institute of Medical Science developed nitroglycerin transdermal patch of coronary heart disease in 157 cases of angina pectoris, the results are as follows.