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目的：观察榄香烯乳（Ｌｘ）联合化疗治疗急性白血病疗效。方法：用榄香烯乳（Ｌｘ）联合化疗治疗急性白血病１８例。其中６例为急性淋巴细胞白血病（ＡＬＬ），１２例为急性非淋巴细胞白血病（ＡＮＬＬ）。用法为Ｌｘ３００ｍｇ～５００ｍｇ加入生理盐水５００ｍｌ中每日静滴，持续用１０～１５天，同时联合ＨＡ／ＤＡ或ＶＤＰ方案化疗。对照组２０例，其中８例为（ＡＬＬ），１２例为（ＡＮＬＬ）；化疗方案及用量同治疗组。结果：治疗组ＣＲ率为７２２％，对照组ＣＲ率５５０％（Ｐ＜００５），治疗组有效率９４４％，对照组有效率７５０％（Ｐ＜００１）。结论：Ｌｘ对急性白血病有肯定疗效，且无骨髓抑制，对肝、肾、心脏无毒性反应，在化疗后白细胞、血小板减少时，仍能使用榄香烯乳。
OBJECTIVE: To observe the effect of elemene emulsion (Lx) combined with chemotherapy on acute leukemia. Methods: Eleven leucene milk (Lx) combined with chemotherapy was used to treat 18 cases of acute leukemia. Of these, 6 were acute lymphoblastic leukemia (ALL) and 12 were acute nonlymphocytic leukemia (ANLL). The use of Lx300mg ~ 500mg added to normal saline 500ml daily infusion, continued for 10 to 15 days, combined with HA / DA or VDP chemotherapy. The control group consisted of 20 patients, of whom 8 were ALL and 12 were ANLL; the chemotherapy regimen and dosage were the same as the treatment group. Results: The CR rate in the treatment group was 72. 2%, the CR rate in the control group was 55.0% (P<0. 05), the treatment group was 94.4%, and the control group efficiency was 75.0% (P<0. 01). Conclusion: Lx has a positive effect on acute leukemia and no bone marrow suppression. It has no toxic reaction to liver, kidney and heart. Elemene milk can still be used when leukocytes and platelets decrease after chemotherapy.